Located in the heart of Europe, the Grand Est Region is sharing borders with 4 very dynamic countries : Germany, Belgium, Luxembourg and Switzerland. Third industrial region in France, Grand Est is acting to prepare for the Industry of the future and to become one of the European leaders in the bioeconomy. The major regional territory’s assets are various: automotive industry, chemistry-materials, wood-forest, machinery-equipment, health technologies, renewable energy, agro-food and agro-resources industry. Grand Est also pursues two important challenges: first, to implement the « European valley of artificial intelligence », from Dunkirk to Basel; Second to support all companies and stakeholders in their digitalization process. To strengthen regional attractiveness and competitiveness, one of the main competences of French regions, Grand Est promotes research and innovation activities in the region. The higher education and research sector of Grand Est represents 209 000 students, 11 000 researchers from public and private research centres and 180 laboratories.